Instant Pot Mississippi Pot Roast

Juicy, tender, instant pot Mississippi pot roast is melt-in-your-mouth delicious! This pot roast takes just 60 minutes to cook in the instant pot as opposed to 4-8 hours with the other methods.

  • Total 1 hour 5 minutes
  • Serves 6 servings
  • Dinner
  • American
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Instant Pot Mississippi Pot Roast in a bowl

Juicy, tender, instant pot Mississippi pot roast is melt-in-your-mouth delicious! This pot roast takes just 60 minutes to cook in the instant pot as opposed to 4-8 hours with the other methods.

bowl of Instant Pot Mississippi Pot Roast more

Why this recipe works

Making Mississippi pot roast is incredibly easy, especially when it’s made in the instant pot. It cooks into pull-apart tender hunks of flavorful roast with a tangy bite thanks to the pepperoncinis. All you need are 6 ingredients, an instant pot, and an appetite for dinner!

While we’ve also made crockpot Mississippi pot roast that’s slow-cooked to perfection and is a fantastic dump-and-go dinner before work, using the instant pot method is great for when you want dinner ready quicker than a conventional oven or crockpot can give to you when it comes to chuck roast.

Instant Pot Mississippi Pot Roast

Ingredients you will need

Get all measurements, ingredients, and instructions in the printable version at the end of this post.

ingredients for Instant Pot Mississippi Pot Roast

ROAST – When choosing a chuck roast, grab a well-marbled cut of meat. Having a marbled cut of meat adds more flavor as the fat melts into the roast while it cooks. If you would like, you can brown the chuck roast in a pan before adding it to the instant pot, this will help retain the moisture of the meat and you guessed it, add more flavor. This isn’t a necessary step, but it’s one you can choose to do if you want!

PEPPERS – Pepperoncini peppers add so much flavor and the vinegar from the brine helps to tenderize and balance the richness. They aren’t spicy once they’ve cooked for several hours, all that’s left is a little zip in the juice and roast. If you’re concerned about spice, try it with just the pepperoncini juice instead but we don’t recommend leaving out pepperoncini peppers or juice altogether!

SEASONINGS – Ranch seasoning packets can be found at your local grocery store, or you can opt to make your own homemade ranch seasoning mix in its place. Don’t forget the au jus gravy packet! The butter is completely optional, but it enriches the gravy.

How to Make Instant Pot Mississippi Pot Roast

These step by step photos and instructions are here to help you visualize how to make this recipe. You can Jump to Recipe to get the printable version of this recipe, complete with measurements and instructions at the bottom.

  1. Place the chuck roast in a 6 quart instant pot.

    EXPERT TIP – You can optionally brown the meat in a pan before adding if you’d like, but it is not imperative to the recipe.
  2. Sprinkle with seasonings and butter.chuck roast with seasonings and pepperoncinis in instant pot
  3. Pour the beef broth, pepperoncinis, and pepperoncini juice along the side into the bottom of the instant pot.mississippi pot roast in an instant pot
  4. Cook on high pressure for 60 minutes.
  5. Natural-release pressure, shred, return to pot, and serve as desired.shredded chuck roast on cutting board

Frequently Asked Questions & Expert Tips

Can I use a frozen roast?

Yes, you can use a frozen roast, however, you may need to add additional time to allow the meat to cook thoroughly. Cook until meat is pull-apart tender.

How to store Mississippi pot roast?

You can store Mississippi pot roast in an air tight container kept in the refrigerator for 3-4 days.

Can I make it ahead and freeze?

Yes, Mississippi pot roast can be made ahead of time and frozen for 5-6 months. Simply remove from the freezer and allow to thaw in the refrigerator before reheating. When reheating, we like to add some water or even broth to add moisture back to the beef. Reheat on the stovetop, in the oven, or in the microwave.

Instant Pot Mississippi Pot Roast with mashed potatoes

Serving Suggestions

We love serving Mississippi pot roast with a heaping scoop of mashed potatoes, egg noodles, or rice. As we’ve mentioned in our slow cooker pot roast recipe, you can even make Mississippi pot roast sandwiches out of it. Slice a French baguette or sub roll in half, add the shredded roast, your favorite cheese, and extra peppers if desired. Dip in the gravy for a delicious meal!

There’s nothing we like more than simple, flavorful meals that are easy enough for everyone to make. This instant pot Mississippi pot roast fits the bill perfectly, and is sure to impress even the pickiest of eaters.

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